Skip to content

Health and biomarkers data

Understanding Society collects information about participants’ social and economic circumstances, attitudes and beliefs and it also gathers information about their health. 

As part of the main survey, from Wave 1 onwards participants are asked multiple questions about their general health, self-reported health conditions and health behaviours. The Study also includes a number of validated scales that collect information on:

  • mental health (General Health Questionnaire-12) 
  • measures of wellbeing WEMWBS
  • quality of life, physical and mental health (SF-12) 
  • alcohol consumption (CAGE)
  • exercise (IPAQ)
  • children’s mental health (SDQ strengths and difficulties questionnaire) 

      We ask different age groups and demographics additional questions: 

      • Young adults 16-21 are asked about smoking, alcohol and recreational drug use.  
      • Children 10-15 complete a paper self-completion questionnaire about disability, nutrition, exercise, mental health, smoking and alcohol consumption.  For children under 10 years, parents are asked about key development stages at ages 3, 5 and 8. For ease the PEACH data file brings this data together
      • Women are asked about their health and behaviour during pregnancy, child birth, birth weight, breast feeding and early indicators of an infant’s health.

      To find out about the variables in the Study use the index terms to search for health and wellbeing variables including health behavioursubjective wellbeing and personal health condition.

        Understanding Society also has omics data. Find out more about the data available and how to apply for them in the omics web area.

        Waves 2 and 3 nurse collected data

        In Wave 2 and Wave 3 adult participants received a follow-up visit from a research nurse. A range of bio-measures were collected from around 13,500 adults, which included blood pressure, weight, height, waist measurement, body fat, grip strength and lung function. 

        Blood samples were also taken at these visits and biomarker data is available including: 

        • Measures of fat in the blood (cholesterol and triglycerides
        • An indicator of diabetes (Glycated haemoglobin HbA1c
        • Measures of inflammation and the immune system– the body’s way of responding to harm (High sensitivity c-reactive protein, fibrinogen and CMV seropositivity) 
        • Measures of anaemia (Haemoglobin and ferritin
        • Liver and kidney function 
        • Hormones that build up the body – (testosterone, DHEAs, IFG-1). 

                In Wave 16 (in the field 2024-2026) we will be collecting further biological data from our participants. This will include blood samples, blood pressure, weight, height and waist measurements. These data will be released towards the end of 2026. To stay updated, please subscribe to our newsletter.

                Proteomic panels

                Proteomics is the analysis of a large set of protein molecules. Data from Understanding Society has been used to create two proteomic panels: one for proteins from the cardiometabolic panel and one for proteins in the neurology panel.

                The cardiometabolic panel focuses on cardiovascular health (heart and blood vessels) and metabolic health, for example diabetes. The neurological panel focuses on proteins involved in areas such as brain development and neurodegenerative disease. Read more about the proteomic panels in the User Guide.

                Epigenetic ageing algorithms (epigenetic clocks)

                Differences between actual age and biological age may be related to life circumstances and environment. For the Understanding Society data, five epigenetic ageing algorithms have been constructed. You can read more about epigenetic ageing algorithms in the User Guide

                Ageing algorithm and proteomic panel data is available from the UK Data Service in the Nurse health assessment dataset, SN: 7251

                Polygenic scores 

                A polygenic score is a continuous variable that reflects an individual’s propensity towards a given trait. These traits can include disease status, behaviours, and blood levels of biomolecules, among many others.  

                A number of polygenic score variables have been derived from the genomic dataset and are available for the first time in the Special Licence version of the Nurse Assessment dataset (SN 7587). Polygenic scores generated in Understanding Society can be used as explanatory variables in a range of analyses, including investigating the causal effect of the polygenic score trait with health or social outcomes. However, any findings from analyses that use polygenic scores as explanatory variables require careful interpretation. Please consult the User Guide for information on using these data appropriately

                Polygenic scores data are available from the UK Data Service in the Special Licence version of the Nurse Health Assessment dataset, SN: 7587.

                Biomeasures collected using the Innovation Panel

                The Innovation Panel is used to collect new types of health and wellbeing data. Respondents have been asked to provide:

                  • finger measurements so investigate prenatal testosterone exposure effects on human development
                  • a hair sample from which hair cortisol, hair cortisone, hair progesterone, and hair testosterone were extracted
                  • a dried blood sample. The data coded from these samples include dried blood triglycerides, dried blood cholesterol, dried blood high-density lipoprotein cholesterol, and dried blood glycated haemoglobin.
                  • pre-interview blood pressure readings
                  • body-volume index, using an app

                  Innovation Panel respondents have also been invited to use a cognition app using a navigation game and a wellbeing app to record their wellbeing each day.

                  Health and wellbeing data from the Innovation Panel is available to download. See the Innovation Panel area for more details.

                  COVID serology collection

                  The COVID Study data collection includes COVID antibody testing carried out in March 2021. These data are available in the COVID-19 dataset. See the COVID-19 data area for more details.

                  Email newsletter

                  Sign up to our newsletter